Pilot program
An initial VICA™ pilot lets your team evaluate the method using its own samples, whether you need to compare candidates, examine a target interaction or test the effect of sample conditions. Pavonis reviews that requirement and proposes the measurements and deliverables, then runs the agreed study alongside your existing assays without an instrument purchase.
Process
Start with a non-confidential description of the interaction, previous findings and measurements you need. This gives our team the scientific context for reviewing the proposed experiment.
Using that research context, we review your targets, candidates or specimens and the relevant sample conditions. We can then identify suitable VICA™ formats and explain the technical limitations affecting the proposed measurements.
Once the assay requirements are understood, we agree on the work, outputs, sample requirements, timing and price. Confidentiality and handling arrangements are settled at this stage, before proprietary information or material is exchanged.
After performing the study, Pavonis returns the agreed measurements and analysis. We review the findings with you to discuss which candidates may warrant further characterization or which conditions need another experiment.
9Bio progressed from a VICA™ pilot to paid studies with Pavonis after using the platform in its discovery program.
Scope and terms
The target, previous findings, comparisons, assay format and controls
Sample types, quantities, preparation and confidentiality arrangements
The measurements, analysis and review of findings
Timing and price for the agreed work
Target and assay suitability are reviewed before a pilot is agreed. Results describe the tested interactions and conditions, not clinical performance.
Send a non-confidential description of the target or candidates, the binding measurements you need and the samples available. From that outline, we can review the technical requirements and discuss a pilot proposal. Physical samples should follow only after handling arrangements have been agreed.